MCell and DReAMM People: Stephen D. Meriney
Stephen D. Meriney, Ph.D.
Associate Professor, Depts. of Psychiatry and Neuroscience
University of Pittsburgh
Education
B.A., Zoology, University of New Hampshire
Ph.D., Physiology/Neuroscience, University of Connecticut
Post-doc Training: Synaptic physiology and biophysics, Dr. Alan Grinnell, UCLA School of Medicine
Role at CQBS
Microphysiological research
Dr. Meriney is a physiologist with research interests in ion channel function and modulation, and the regulation of transmitter release from nerve terminals. His laboratory uses various model organisms to study synaptic physiology and ion channel function including two frog species (Rana pipiens and Xenopus laevis) that provide the physiological data used in MCell microphysiological modeling in collaboration with Dr. Joel Stiles. Currently, students in Dr. Meriney's laboratory use MCell modeling approaches to test mechanistic hypotheses to help explain some effects of pharmacologic agents on transmitter release and short-term plasticity at the synapse.
MCell 3.3 and DReAMM 3.3.0 Now Available
New versions for Linux and Mac OS X now available on our Downloads page.
MCell Used in New Vesicle Fusion Findings
Researchers at the National Institute of Neurological Disorders and Stroke use MCell to simulate "kiss-and-run" fusion at calyx-type synapses. See He, L., et al. Two modes of fusion pore opening revealed by cell-attached recordings at a synapse. Nature 444, 102-105 (2006).
MCell and DReAMM Demographics and Teaching Statistics
Check out CQBS's most recent usage statistics. [Read more]