CQBS Research
Research at the CQBS focuses on spatially realistic cell modeling in biomedicine, using Monte Carlo and hybrid simulation algorithms coupled to specialized model construction, editing, and visualization tools. Research thus falls into two interconnected categories, software development and biomedical application projects.
Software Development
Biomedical Application Projects
- Presynaptic calcium dynamics and neurotransmitter release
- Biophysical factors underlying the variability of synaptic signals
- Simulation of oscillating biochemical networks
- Simulation of ion-selective electrode measurements of single ion channel properties
Selected Publications
MCell 3.3 and DReAMM 3.3.0 Now Available
New versions for Linux and Mac OS X now available on our Downloads page.
MCell Used in New Vesicle Fusion Findings
Researchers at the National Institute of Neurological Disorders and Stroke use MCell to simulate "kiss-and-run" fusion at calyx-type synapses. See He, L., et al. Two modes of fusion pore opening revealed by cell-attached recordings at a synapse. Nature 444, 102-105 (2006).
MCell and DReAMM Demographics and Teaching Statistics
Check out CQBS's most recent usage statistics. [Read more]