Pittsburgh Supercomputing Center

National Resource for Biomedical Supercomputing

Carnegie Mellon University

The Salk Institute
Howard Hughes Medical Institute

National Institute of Health

National Center for Research Resources

National Institute of General Medical Sciences

National Science Foundation

About MCell and DReAMM

MCell and DReAMM development is an ongoing collaboration between the Center for Quantitative Biological Simulation at the Pittsburgh Supercomputing Center and the Computational Neurobiology Laboratory at the Salk Institute, with support from the National Institutes of Health, the Howard Hughes Medical Institute, and the National Science Foundation.

About MCell

Cells are tightly packed with structures and molecules that carry out the day-to-day operations of living. Understanding how cellular design dictates function is essential to understanding life and disease, in the brain, heart, or elsewhere. MCell (Monte Carlo cell) is a program that uses spatially realistic 3-D cellular models and specialized Monte Carlo algorithms to simulate the movements and reactions of molecules within and between cells—cellular microphysiology.


About DReAMM

Model design, editing, and visualization are integral to microphysiological simulations. DReAMM (Design, Render, and Animate MCell Models) can be used to import and edit meshes from 3-D reconstruction and computer-aided-design software, and subsequently tailor the meshes to represent pieces of cells in MCell simulations. In addition, it is used to visualize MCell simulation results, including the locations and states of participating meshes and molecules.